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Tetrabromophthalic anhydride → 2,3,4,5-Tetrabromo-6-[(4-chloro-3-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tetrabromophthalic anhydride | HCID 12443 | — |
| 反応物 | Isopropyl 5-amino-2-chlorobenzoate | HCID 369590 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 2,3,4,5-Tetrabromo-6-[(4-chloro-3-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid | HCID 507316 | 87% |
反応手順
Tetrabromophthalic anhydride (7.03 g, 0.015 mole), 1-methylethyl 5-amino-2-chlorobenzoate (3.24 g, 0.015 mole) and toluene (about 150 ml) were heated almost to reflux over 30 minutes. The reaction mixture was cooled and filtered to give the title compound, m.p. 169°-171° C. (decomp.) (8.92 g, 87% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05268389 |
| 出典データセット | uspto-grants-1993_12 |
| ORD ID | ord-28d9383bf766479eb480eb2c911469f3 |
| 出典メモ | uspto-grants-1993_12 |