1-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1) → 3-(Dimethylamino)-1-phenyl-1-propanone

HRID 326399

反応式

HRID 326399 の反応式
Cl.[CH3:2][N:3]([CH3:14])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7].C(=O)(O)[O-].[Na+]>ClCCl>[CH3:14][N:3]([CH3:2])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7]

参加物

4

反応物 2

HCID 928441-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1)HCID 516892Sodium Bicarbonate

生成物 1

HCID 770423-(Dimethylamino)-1-phenyl-1-propanone収率 95.3%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

3-Dimethylaminopropiophenone hydrochloride (20 g) was treated with aqueous sodium bicarbonate solution in dichloromethane. The layers were separated and the organic phase was dried over anhydrous magnesium sulfate, filtered, and the filtrate was evaporated to provide 15.8 g of 3-dimethylaminopropiophenone.

後処理

  1. customThe layers were separated
  2. dry with materialthe organic phase was dried over anhydrous magnesium sulfate
  3. filtrationfiltered
  4. customthe filtrate was evaporated

出典と根拠

ORDレコード
ord-8405d6c06e7a480280c47c4f322f1fd8
出典データセット
uspto-grants-1993_12
特許番号
US05268468

関連ノート

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