関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Carbamic acid, ethyl ester | HCID 5641 | — |
| 反応物 | N,N-Dimethylbenzylamine | HCID 7681 | — |
| 反応物 | Oxirane, 2-[(octadecyloxy)methyl]- | HCID 61831 | — |
| 触媒 | Di-n-butyldilauryltin | HCID 9809426 | — |
| 生成物 | 5-Stearyloxymethyl-2-oxazolidinone | HCID 19736927 | 290.8% |
反応手順
4.45 g (0.050 mole) of ethyl carbamate was dissolved in 16.3 g (0.050 mole) of stearyl glycidyl ether. After adding 2.0 g of N, N-dimethylbenzylamine and 2.0 g of di-n-butyltin dilaurate, the solution was heated at 160° C. for 1 hour while blowing nitrogen gas into the reaction mixture. The product was purified by silica gel column chromatography (developing solvent, hexane: ethyl acetate=4:1) to give 15.9 g (85% of theory) of 5-stearyloxymethyl-2- oxazolidinone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05268484 |
|---|
| 出典データセット | uspto-grants-1993_12 |
|---|
| ORD ID | ord-5e4d94a8c621480da7a0c4d4efebc675 |
|---|
| 出典メモ | uspto-grants-1993_12 |
|---|
