化工社化工社 化学情報印刷レポート · 研究参考用
4-Hydroxybenzoic Acid → Benzoic acid, 4-hydroxy-, 2-methylbutyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Hydroxybenzoic Acid | HCID 135 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | (S)-2-methyl-1-butanol | HCID 2723602 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Benzoic acid, 4-hydroxy-, 2-methylbutyl ester | HCID 13530949 | 88.1% |
反応手順
0.29 mol (40.0 g) of p-hydroxybenzoic acid and 0.35 mol (30.9 g) of (S)-(-)-2-methylbutanol were refluxed for 20 hours in 150 ml of toluene in the presence of 1 ml of concentrated sulfuric acid. The reaction solution was concentrated and then purified by column chromatography to obtain 53.2 g of 2-methylbutyl p-hydroxybenzoate [[α]D23 =+4.95° (CHCl3)]. (Yield: 88%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05269963 |
| 出典データセット | uspto-grants-1993_12 |
| ORD ID | ord-0d3bd3927e224cca824885a3a92f8176 |
| 出典メモ | uspto-grants-1993_12 |