化工社化工社 化学情報印刷レポート · 研究参考用
Benzoic Acid → 2-Chloro-5-cyclopropylmethanesulfonyl-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoic Acid | HCID 243 | — |
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | Bromomethylcyclopropane | HCID 81503 | — |
| 反応物 | 2-Chloro-5-sulfino-benzoic acid | HCID 15112904 | — |
| 溶媒 | Cyclopropanemethanol | HCID 75644 | — |
| 生成物 | 2-Chloro-5-cyclopropylmethanesulfonyl-benzoic acid | HCID 43560564 | 8% |
反応手順
The title compound was synthesised according to the procedure described for the synthesis of 2-Chloro-5-methanesulfonyl)-benzoic acid from 2-Chloro-5-sulfino-benzoic acid and Bromomethyl-cyclopropane (+catalytic amount I2) in 20 ml cyclopropyl methanol/20 ml water and obtained in 8% yield. MS (m/e): 273.1 (MH−, 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07427612B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-6074aae533fb4a4fa4fccb4f830f50df |
| 出典メモ | uspto-grants-2008_09 |