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Pyrrolidine → 5-(Cyclopropylmethyl-sulfamoyl)-2-pyrrolidin-1-yl-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyrrolidine | HCID 31268 | — |
| 反応物 | 2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid | HCID 29035580 | — |
| 反応物 | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| 生成物 | 5-(Cyclopropylmethyl-sulfamoyl)-2-pyrrolidin-1-yl-benzoic acid | HCID 59793495 | 38% |
反応手順
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid and pyrrolidine and obtained in 38% yield. MS (m/e): 323.2 (MH−, 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07427612B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-04a9c757ff6849db868de1d25524796e |
| 出典メモ | uspto-grants-2008_09 |