関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Sodium Cyanide | HCID 8929 | — |
| 反応物 | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 3,4,5-Trimethoxyphenylacetonitrile | HCID 25887 | — |
反応手順
3,4,5-trimethoxy benzyl chloride 7.0 g and sodium cyanide 6.3 g were dissolved into 50 ml of N,N-dimethylformamide and they were then stirred at 80° C. for 45 minutes. The temperature of the reactive liquid was then lowered down to the room temperature, 200 ml of water was added thereto and then extraction was made thrice by means of 100 ml of ethyl acetate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05273985 |
|---|
| 出典データセット | uspto-grants-1993_12 |
|---|
| ORD ID | ord-952544069fad4375a8343463edfcc445 |
|---|
| 出典メモ | uspto-grants-1993_12 |
|---|
