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HRID 32751作成日:2026年10月26日

Thiomorpholine → (5-Methanesulfonyl-2-thiomorpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

https://huagongshe.com/reaction/32751

反応式

関与物質

役割名称HCID仕込み量
反応物ThiomorpholineHCID 67164—
反応物(2-Chloro-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanoneHCID 59793689—
生成物(5-Methanesulfonyl-2-thiomorpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanoneHCID 68839402—

反応手順

The title compound was prepared according to the procedure described for example 202 from (2-Chloro-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (example BO) and thiomorpholine to yield the title compound as a pale yellow solid. MS (m/e): 514.5 (M+H, 100%).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07427612B2
出典データセットuspto-grants-2008_09
ORD IDord-94a98c0f3a1b432f8125232cf1cfd8b4
出典メモuspto-grants-2008_09