7-Chloro-2-hydrazinyl-5-phenyl-3H-1,4-benzodiazepine → 7-chloro-2-[(2-chloro-2-vinyl-1-methylethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine

HRID 328108ノート

反応式

HRID 328108 の反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1.[Cl:21][CH:22]([CH:26]=[CH2:27])[C:23](=O)[CH3:24]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][N:13]=[C:26]([CH3:27])[CH:22]([Cl:21])[CH:23]=[CH2:24])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1

参加物

3

反応物 2

HCID 123908747-Chloro-2-hydrazinyl-5-phenyl-3H-1,4-benzodiazepineHCID 214439873-Chloro-4-penten-2-one

生成物 1

HCID 572255807-chloro-2-[(2-chloro-2-vinyl-1-methylethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine

実験手順

In the manner given in Example 1, 7-chloro-2-hydrazino -5-phenyl-3H-1,4-benzodiazepine can be reacted with 3-chloro-4-penten-2-one to give 7-chloro-2-[(2-chloro-2 -vinyl-1-methylethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine.

出典と根拠

ORDレコード
ord-170dda2d13bb46f892b84d3ab355f9c2
出典データセット
uspto-grants-1977_04
特許番号
US04016165

反応ノート

読み込み中…