Triethylamine → HCID 21444454、化合物

HRID 328231ノート

反応式

HRID 328231 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7][C:8]1[C:13]([CH3:14])=[CH:12][C:11]([OH:15])=[CH:10][C:9]=1[CH3:16].[CH3:17][N:18]=[C:19]=[O:20].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:17][NH:18][C:19](=[O:20])[O:15][C:11]1[CH:10]=[C:9]([CH3:16])[C:8]([S:7][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)=[C:13]([CH3:14])[CH:12]=1

参加物

5

反応物 3

HCID 8471Triethylamine2 回HCID 12228Methyl Isocyanate2 回HCID 214444563,5-Dimethyl-4-[(pyridin-2-yl)sulfanyl]phenol

生成物 1

HCID 21444454HCID 21444454、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

4-(2-Pyridylthio)-3,5-dimethylphenol (161 g.), prepared in part A, and methylisocyanate (48 g.) was dissolved in dry toluene (1500 ml.) containing triethylamine (10 ml.) and the mixture was then stirred under reflux overnight. Further quantities of methyl isocyanate (22 g.) and triethylamine (10 ml.) were then added and refluxing was continued for a further 6 hours.

後処理

  1. temperatureunder reflux overnight
  2. temperaturerefluxing

出典と根拠

ORDレコード
ord-f3409fc254964ee69152ca37335f6d2d
出典データセット
uspto-grants-1977_04
特許番号
US04016278

反応ノート

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