Acetic Anhydride → 5-(Trifluoromethyl)isobenzofuran-1,3-dione
反応式
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]([C:12]([OH:14])=[O:13])[C:6](=[CH:10][CH:11]=1)[C:7](O)=[O:8].C(OC(=O)C)(=O)C>>[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]2[C:12](=[O:14])[O:13][C:7](=[O:8])[C:6]2=[CH:10][CH:11]=1参加物
3
実験手順
4-Trifluoromethyl-phthalic acid (106.6 g.) and acetic anhydride (215 cc.) are heated to the reflux temperature for 30 minutes. After concentration under reduced pressure (30 mm Hg), the residue is stirred with cyclohexane (420 cc.). After filtration and drying, 4-trifluoromethyl-phthalic anhydride (73.5 g.) melting at 54° C is obtained.
後処理
- concentrationAfter concentration under reduced pressure (30 mm Hg)
- filtrationAfter filtration
- customdrying
出典と根拠
- ORDレコード
- ord-6eae555cb5c84c91b3e011b3515d54ee
- 出典データセット
- uspto-grants-1977_04
- 特許番号
- US04016274
反応ノート
読み込み中…