Dodecanoyl chloride → 2-[Methyl(4-methylbenzoyl)amino]ethyl dodecanoate

反応式

[CH3:1][N:2]([CH2:12][CH2:13][OH:14])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][CH:6]=1)=[O:4].[C:15](Cl)(=[O:27])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>>[CH3:1][N:2]([CH2:12][CH2:13][O:14][C:15](=[O:27])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][CH:6]=1)=[O:4]

参加物

反応物 2

HCID 8166Dodecanoyl chloride

HCID 21441887N-(2-hydroxyethyl)-N,4-dimethylbenzamide

生成物 1

HCID 214418812-[Methyl(4-methylbenzoyl)amino]ethyl dodecanoate

実験手順

N-methyl-N-(2-lauroyloxyethyl)-p-toluamide was prepared by the procedure of example 1 from 19 gms. (0.1 mole) of N-methyl-N-(2-hydroxyethyl)-p-toluamide and 22 gms. (0.1 mole) of lauroyl chloride. The structure of the final product was characterized on the basis of IR and NMR spectral analyses as described in example 1.

後処理

customN-methyl-N-(2-lauroyloxyethyl)-p-toluamide was prepared by the procedure of example 1 from 19 gms

出典と根拠

ORDレコード: ord-18cfc6ff3a2249b884f95b49c1629176
出典データセット: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04017522

反応ノート

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