Water → 1-p-Ethoxyphenyl-1-p-ethylphenyl-2-nitro-n-hexane

HRID 328600

反応式

HRID 328600 の反応式
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9](O)[CH:10]([N+:15]([O-:17])=[O:16])[CH2:11][CH2:12][CH2:13][CH3:14])=[CH:5][CH:4]=1)[CH3:2].[CH2:19]([O:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH3:20].S(=O)(=O)(O)O.O>C(Cl)Cl>[CH2:19]([O:21][C:22]1[CH:27]=[CH:26][C:25]([CH:9]([C:6]2[CH:7]=[CH:8][C:3]([CH2:1][CH3:2])=[CH:4][CH:5]=2)[CH:10]([N+:15]([O-:17])=[O:16])[CH2:11][CH2:12][CH2:13][CH3:14])=[CH:24][CH:23]=1)[CH3:20]

参加物

6

反応物 4

HCID 962WaterHCID 1118Sulfuric AcidHCID 7674PhenetoleHCID 214435651-p-Ethylphenyl-2-nitro-1-hexanol

生成物 1

HCID 214435611-p-Ethoxyphenyl-1-p-ethylphenyl-2-nitro-n-hexane

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

25.1 g of 1-p-ethylphenyl-2-nitro-1-hexanol and 14.6 g of ethoxybenzene are dissolved in 80 ml of methylene chloride, and the solution is added dropwise at 0° C, with vigorous stirring, to 90 g of conc. sulphuric acid and 10 ml of water. After 2 hours' stirring at room temperature, the mixture is poured on to 400 ml of ice water. The product is taken up in methylene chloride and washed with saturated sodium bicarbonate solution. After the solvent has been removed by evaporation, the oil remaining behind is dried in high vacuum at 60° C for 2 hours. There is obtained the compound of the formula ##STR7## as viscous, dark yellow oil having a refractive index of nD22 = 1.5452.

後処理

  1. washwashed with saturated sodium bicarbonate solution
  2. customAfter the solvent has been removed by evaporation
  3. customthe oil remaining behind is dried in high vacuum at 60° C for 2 hours
  4. customThere is obtained the compound of the formula ##STR7## as viscous, dark yellow oil

出典と根拠

ORDレコード
ord-7b06222b4bb64113b1dac437e09fdfa4
出典データセット
uspto-grants-1977_04
特許番号
US04017640

関連ノート

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