反応式
[C:1]([C:3]1[C:4]([CH3:9])=[N:5][CH:6]=[CH:7][CH:8]=1)#[N:2].[C:10]([C:12]1[C:13]([CH2:18][CH3:19])=[N:14][CH:15]=[CH:16][CH:17]=1)#[N:11].[C:20](C1C(CC2C=CC=CC=2)=NC=CC=1)#N.C(C1C(CCC2C=CC=CC=2)=NC=CC=1)#N.C(C1C(CC(C2C=CC=CC=2)C)=NC=CC=1)#N>>[NH2:2][C:1]1[C:3]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[C:9]([CH3:20])=[C:10]([C:12]2[C:13]([CH2:18][CH3:19])=[N:14][CH:15]=[CH:16][CH:17]=2)[N:11]=1参加物
実験手順
In a similar manner by substituting the 3-cyano-2-methylpyridine with equivalent quantities of 3-cyano-2-ethylpyridine, 3-cyano-2-benzylpyridine, 3-cyano-2-phenethylpyridine and 3-cyano-2-phenylpropylpyridine and by substantially following the procedure of this example there is produced 1-amino-3(2-ethyl-pyridyl)-4-methyl-2,5-naphthyridine; 1-amino-3-(2-benzyl-3-pyridyl)-4-phenyl-2,5-naphthyridine; 1-amino-3-(2-benzyl-3-pyridyl)-4-phenyl-2,5-naphthyridine; 1-amino-3-(2-phenethyl-3-pyridyl)-4-benzyl-2,5-naphthyridine; 1-amino-3-(2-phenylpropyl-3-pyridyl)-4-phenethyl-2,5-naphthyridine, respectively. Similarly, in those instances wherein it is desired to produce those compounds bearing substituents on the pyridyl, phenyl and benzyl moieties of the foregoing then, as expected, the appropriately substituted starting reactants are then similarly reacted.
出典と根拠
- ORDレコード
- ord-75927698f2604792952013a1c30419e7
- 出典データセット
- uspto-grants-1977_04
- 特許番号
- US04017500
関連ノート
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