Potassium Carbonate → 2-Ethyl-3,6,6-trimethyl-1-crotonoyl-2-cyclohexene

HRID 328665ノート

反応式

HRID 328665 の反応式
[CH2:1]([C:3]1[CH:4]([C:12](=[O:16])[CH2:13][CH:14]=[CH2:15])[C:5]([CH3:11])([CH3:10])[CH2:6][CH2:7][C:8]=1[CH3:9])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH2:1]([C:3]1[CH:4]([C:12](=[O:16])/[CH:13]=[CH:14]/[CH3:15])[C:5]([CH3:11])([CH3:10])[CH2:6][CH2:7][C:8]=1[CH3:9])[CH3:2]

参加物

4

反応物 2

HCID 11430Potassium CarbonateHCID 214396681-(2-Ethyl-3,6,6-trimethylcyclohex-2-en-1-yl)but-3-en-1-one

生成物 1

HCID 214396692-Ethyl-3,6,6-trimethyl-1-crotonoyl-2-cyclohexene収率 91.5%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A suspension of 3.5 g (15.9 mmol) of 2-ethyl-3,6,6-trimethyl-1-[but-3-enoyl]-2-cyclohexene and 2.0 g of potassium carbonate in 40 ml of acetone is stirred at room temperature under nitrogen for 24 hours. The salt is removed by filtration and the filtrate concentrated. After fractional distillation, the residue yields 3.2 g (91.5%) of 2-ethyl-3,6,6-trimethyl-1-crotonoyl-2-cyclohexene; boiling point 59°-60° C/0.04 mm Hg; nD 20 = 1.4952.

後処理

  1. customThe salt is removed by filtration
  2. concentrationthe filtrate concentrated
  3. distillationAfter fractional distillation

出典と根拠

ORDレコード
ord-ac78d4c37a6b4c37a7e2e3b07f04b601
出典データセット
uspto-grants-1977_04
特許番号
US04018718

反応ノート

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