Di-tert.-butyl 2-(4-acetoxynonyl)-2-[4-(ethoxycarbonylmethoxy)-butyl]-malonate → Ethyl 5-carboxy-9-acetoxytetradecyloxyacetate

HRID 328773ノート

反応式

HRID 328773 の反応式
C(OC(CCCCC)CCCC(CCCCCCC(OCC)=O)(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)(=O)C.[C:40]([O:43][CH:44]([CH2:74][CH2:75][CH2:76][CH2:77][CH3:78])[CH2:45][CH2:46][CH2:47][C:48]([CH2:63][CH2:64][CH2:65][CH2:66][O:67][CH2:68][C:69]([O:71][CH2:72][CH3:73])=[O:70])(C(OC(C)(C)C)=O)[C:49]([O:51]C(C)(C)C)=[O:50])(=[O:42])[CH3:41]>>[C:49]([CH:48]([CH2:47][CH2:46][CH2:45][CH:44]([O:43][C:40](=[O:42])[CH3:41])[CH2:74][CH2:75][CH2:76][CH2:77][CH3:78])[CH2:63][CH2:64][CH2:65][CH2:66][O:67][CH2:68][C:69]([O:71][CH2:72][CH3:73])=[O:70])([OH:51])=[O:50]

参加物

3

反応物 2

HCID 21317616Di-tert.-butyl 2-(4-acetoxynonyl)-2-[4-(ethoxycarbonylmethoxy)-butyl]-malonateHCID 21317623Di-tert.-butyl 2-(4-acetoxynonyl)-2-(6-ethoxycarbonylhexyl)-malonate

生成物 1

HCID 21317571Ethyl 5-carboxy-9-acetoxytetradecyloxyacetate

実験手順

This compound is prepared essentially by the method described in Example 1, Step D except that the di-tert.-butyl 2-(4-acetoxynonyl)-2-(6-ethoxycarbonylhexyl)-malonate of the example is replaced by di-tert.-butyl 2-(4-acetoxynonyl)-2-[4-(ethoxycarbonylmethoxy)-butyl]malonate. The title compound is purified by column chromatography on silica gel.

後処理

  1. customThis compound is prepared essentially by the method
  2. customThe title compound is purified by column chromatography on silica gel

出典と根拠

ORDレコード
ord-c897eeda90124d5691716300de10eab5
出典データセット
uspto-grants-1977_04
特許番号
US04018802

反応ノート

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