Methyl isothiocyanate → N-(2-dimethylaminoethyl)-N'-[2-(3-isothiazolylmethylamino)ethyl]thiourea
反応式
CN=C=S.[S:5]1[CH:9]=[CH:8][C:7]([CH2:10][NH:11][CH2:12][CH2:13][NH2:14])=[N:6]1.[CH3:15][N:16]([CH3:22])[CH2:17][CH2:18][N:19]=[C:20]=[S:21]>>[CH3:15][N:16]([CH3:22])[CH2:17][CH2:18][NH:19][C:20]([NH:14][CH2:13][CH2:12][NH:11][CH2:10][C:7]1[CH:8]=[CH:9][S:5][N:6]=1)=[S:21]参加物
4
実験手順
By the procedure of Example 40(a) (ii), N-(3-isothiazolylmethyl)ethylenediamine is reacted with 2-dimethylaminoethyl isothiocyanate to give N-(2-dimethylaminoethyl)-N'-[2-(3-isothiazolylmethylamino)ethyl]thiourea. Reacting with hydrobromic acid gives the hydrobromide salt.
出典と根拠
- ORDレコード
- ord-74be08d09354478885c693f42caf7981
- 出典データセット
- uspto-grants-1977_04
- 特許番号
- US04018931
反応ノート
読み込み中…