Hydrochloric Acid → 4-(dimethylamino)-2-hydroxybenzaldehyde

HRID 329206ノート

反応式

HRID 329206 の反応式
[OH:1][C:2]1[CH:7]=[C:6]([N:8]([CH3:10])[CH3:9])[CH:5]=[CH:4][C:3]=1[CH:11]1N(C2C=CC=CC=2)CCN1C1C=CC=CC=1.Cl.[OH2:29]>C(O)C>[OH:1][C:2]1[CH:7]=[C:6]([N:8]([CH3:10])[CH3:9])[CH:5]=[CH:4][C:3]=1[CH:11]=[O:29]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 12265340HCID 12265340、化合物

生成物 1

HCID 98153054-(dimethylamino)-2-hydroxybenzaldehyde

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

The reaction product (XV) obtained in accordance with Example 16 is suspended in warm ethanol. A clear solution is formed, following the addition of 5 ml of 5% aqueous hydrochloric acid. 10 ml of water are added and the aqueous solution is extracted by repeated shaking with 10 ml batches of chloroform. After the chloroform has been distilled off in vacuo from the combined chloroform extracts, 2-hydroxy-4-dimethylaminobenzaldehyde (XVI) is obtained in the form of pale yellow needles, melting at 77° to 78° C.

後処理

  1. customA clear solution is formed
  2. extractionthe aqueous solution is extracted
  3. distillationAfter the chloroform has been distilled off in vacuo from the combined chloroform

出典と根拠

ORDレコード
ord-2d017c238cd14073a1c6107aa6c5a48d
出典データセット
uspto-grants-1977_04
特許番号
US04020084

反応ノート

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