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5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid → 5H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid | HCID 12398821 | — |
| 反応物 | 2-carboxy-5-oxo-5H-dibenzo[a,d]cycloheptene | HCID 12563001 | — |
| 反応物 | ethyl (5-oxo-5H-dibenzo[a,d]cyclohepten-2yl)acetate | HCID 53675848 | — |
| 生成物 | 5H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo- | HCID 173910 | — |
反応手順
The compounds of Formula I can be prepared by conducting an Arndt-Eistert reaction upon 5-oxo-5H-dibenzo[a,d]-cycloheptene-2-carboxylic acid to afford, in various steps thereof, 5-oxo-5H-dibenzo[a,d]cyclohepten -2-acetic acid ethyl ester and 5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid. 2-(5-Oxo-5H-dibenzo[a,d]cyclohepten-2-yl)propionic acid, and the corresponding esters of the aforementioned acids can be obtained via alkylation and/or esterification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04020094 |
| 出典データセット | uspto-grants-1977_04 |
| ORD ID | ord-a275555ec09a492aaebc45e7412fac3b |
| 出典メモ | uspto-grants-1977_04 |