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HRID 329319作成日:2026年10月24日

5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid → 5H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo-

https://huagongshe.com/ja/reaction/329319

反応式

関与物質

役割名称HCID仕込み量
反応物5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acidHCID 12398821—
反応物2-carboxy-5-oxo-5H-dibenzo[a,d]cyclohepteneHCID 12563001—
反応物ethyl (5-oxo-5H-dibenzo[a,d]cyclohepten-2yl)acetateHCID 53675848—
生成物5H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo-HCID 173910—

反応手順

The compounds of Formula I can be prepared by conducting an Arndt-Eistert reaction upon 5-oxo-5H-dibenzo[a,d]-cycloheptene-2-carboxylic acid to afford, in various steps thereof, 5-oxo-5H-dibenzo[a,d]cyclohepten -2-acetic acid ethyl ester and 5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid. 2-(5-Oxo-5H-dibenzo[a,d]cyclohepten-2-yl)propionic acid, and the corresponding esters of the aforementioned acids can be obtained via alkylation and/or esterification.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04020094
出典データセットuspto-grants-1977_04
ORD IDord-a275555ec09a492aaebc45e7412fac3b
出典メモuspto-grants-1977_04