5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid → 5H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo-

HRID 329319

反応式

HRID 329319 の反応式
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][C:11](C(O)=O)=[CH:12][C:7]=2[CH:6]=[CH:5][C:4]2[CH:16]=[CH:17][CH:18]=[CH:19][C:3]1=2.C([O:22][C:23](=[O:41])[CH2:24][C:25]1C=CC2C(=O)C3C=CC=CC=3C=CC=2C=1)C.O=C1C2C=CC(CC(O)=O)=CC=2C=CC2C=CC=CC1=2>>[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][C:11]([CH:24]([CH3:25])[C:23]([OH:41])=[O:22])=[CH:12][C:7]=2[CH:6]=[CH:5][C:19]2[CH:18]=[CH:17][CH:16]=[CH:4][C:3]1=2

参加物

4

反応物 3

HCID 123988215-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acidHCID 125630012-carboxy-5-oxo-5H-dibenzo[a,d]cyclohepteneHCID 53675848ethyl (5-oxo-5H-dibenzo[a,d]cyclohepten-2yl)acetate

生成物 1

HCID 1739105H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo-

実験手順

The compounds of Formula I can be prepared by conducting an Arndt-Eistert reaction upon 5-oxo-5H-dibenzo[a,d]-cycloheptene-2-carboxylic acid to afford, in various steps thereof, 5-oxo-5H-dibenzo[a,d]cyclohepten -2-acetic acid ethyl ester and 5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid. 2-(5-Oxo-5H-dibenzo[a,d]cyclohepten-2-yl)propionic acid, and the corresponding esters of the aforementioned acids can be obtained via alkylation and/or esterification.

後処理

  1. customThe compounds of Formula I can be prepared
  2. customto afford, in various steps

出典と根拠

ORDレコード
ord-a275555ec09a492aaebc45e7412fac3b
出典データセット
uspto-grants-1977_04
特許番号
US04020094

関連ノート

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