2-Thiophenecarboxaldehyde → HCID 70373074、化合物
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:9]2[C:13](=[O:14])[C:12]([CH3:16])([CH3:15])[CH2:11][O:10]2)=[C:4]([Cl:17])[CH:3]=1.[S:18]1[CH:22]=[CH:21][CH:20]=[C:19]1[CH:23]=O>C(O)C>[Cl:17][C:4]1[CH2:3][C:2](=[N:1][CH2:23][C:19]2[S:18][CH:22]=[CH:21][CH:20]=2)[CH:7]=[CH:6][C:5]=1[CH2:8][N:9]1[C:13](=[O:14])[C:12]([CH3:15])([CH3:16])[CH2:11][O:10]1参加物
4
実験手順
This compound was prepared in a manner analogous to that of Example 5, using 1.28 grams (0.005 mole) of 2-[(4-amino-2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone and 0.56 gram (0.005 mole) of thiophene-2-carboxaldehyde in 25 mL of ethanol. The reaction mixture was concentrated under reduced pressure to a residual oil. The oil was dissolved in anhydrous diethyl ether and was dried for two hours with magnesium sulfate. The mixture was filtered, and the filtrate was concentrated under reduced pressure to yield 1.46 grams of 2-[[2-chloro-4-[(thien-2-yl)methylimino]phenyl]-methyl]-4,4-dimethyl-3-isoxazolidinone as an oil.