Hydrochloric Acid → 2-Hydroxy-3,4-dimethyl-2-cyclopenten-1-one
反応式
C[O:2][C:3]1[C:4](=[O:10])[CH2:5][CH:6]([CH3:9])[C:7]=1[CH3:8].Cl>>[OH:2][C:3]1[C:4](=[O:10])[CH2:5][CH:6]([CH3:9])[C:7]=1[CH3:8]参加物
3
実験手順
0.70 g (5 mmol) of crude 2-methoxy-3,4-dimethyl-2-cyclopenten-1-one is held at reflux temperature for 3 hours with 7 g (10 fold amount by weight) of 5N hydrochloric acid. The reaction mixture is extracted 3 times with 50 ml of CH2Cl2 each time. The combined organic phases are dried over magnesium sulphate and concentrated on a rotary evaporator to give 0.45 g (71.4%) of 2-hydroxy-3,4-dimethyl-2-cyclopenten-1-one, content 90.6%. The data for this material are:
後処理
- extractionThe reaction mixture is extracted 3 times with 50 ml of CH2Cl2 each time
- dry with materialThe combined organic phases are dried over magnesium sulphate
- concentrationconcentrated on a rotary evaporator
出典と根拠
- ORDレコード
- ord-6d05db3d9a4c4f8da3858e4d157754a1
- 出典データセット
- uspto-grants-1990_01
- 特許番号
- US04892966
反応ノート
読み込み中…