関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Benzyl 4-Hydroxybenzoate | HCID 7180 | — |
| 反応物 | alpha,alpha'-Dichloro-p-xylene | HCID 12171 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1,4-Bis(p-carbobenzyloxyphenoxymethyl)benzene | HCID 14323671 | 33.2% |
反応手順
To a solution of p-hydroxybenzoic acid benzyl ester (68.4 g, 0.3 mol) in N,N-dimethylformamide (274 g) sodium carbonate (15.9 g, 0.15 mol) was added, and stirred at 100° C. Then, p-xylylenedichloride (26.2 g, 0.15 mol) was added to the reaction mixture in 10 minutes, and stirred at 100° C. for one hour. Water was added to the resultant to separate a clued precipitate. The precipitate was filtered, added to N,N-dimethylformamide to be dissolved at 90° C., cooled, filtered, and dried to give a white crystal of 1,4-bis(p-carbobenzyloxyphenoxymethyl)benzene (27.8 g, yield 33.0): m.p. 154°-157° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04894359 |
|---|
| 出典データセット | uspto-grants-1990_01 |
|---|
| ORD ID | ord-5d57cfe81a4249d7acd7f41e61b5abc6 |
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| 出典メモ | uspto-grants-1990_01 |
|---|
