Acetone → Ethyl 2,4-dioxovalerate

HRID 330061

反応式

HRID 330061 の反応式
[CH3:1][C:2]([CH3:4])=[O:3].[C:5]([O:12][CH2:13][CH3:14])(=[O:11])[C:6]([O:8]CC)=O.C(OC(OCC)OCC)C.[Cl-].[NH4+]>C(O)C>[CH3:14][CH2:13][O:12][C:5]([C:6]([CH2:1][C:2]([CH3:4])=[O:3])=[O:8])=[O:11]

参加物

6

反応物 4

HCID 180AcetoneHCID 7268Diethyl OxalateHCID 25517Ammonium ChlorideHCID 31214Ethyl orthoformate

生成物 1

HCID 69208Ethyl 2,4-dioxovalerate

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Ethyl acetopyruvate was prepared from acetone and diethyl oxalate as described in Org. Synthesis, Coll. Vol. 1, 238 (1958). Further reaction with triethylorthoformate and ammonium chloride in ethanol afforded the known enol ether 1. See L. Claisen, Chem. Ber., 40, 3903 (1907).

後処理

  1. customSynthesis, Coll

出典と根拠

ORDレコード
ord-f6734b59d09746dda665bd65287785b5
出典データセット
uspto-grants-1990_01
特許番号
US04894456

関連ノート

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