化工社化工社 化学情報印刷レポート · 研究参考用
Deferiprone → ZINC 3-hydroxy-1,2-dimethylpyrid-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Deferiprone | HCID 2972 | — |
| 反応物 | ZINC 1-ethyl-3-hydroxypyrid-2-one | HCID 70373874 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | ZINC 3-hydroxy-1,2-dimethylpyrid-4-one | HCID 70373691 | — |
反応手順
The procedure described under (A) is followed with 3-hydroxy-1,2-dimethylpyrid-4-one in place of 1-ethyl-3-hydroxypyrid-2-one to give the neutral 2:1 complex from ethanol as a white crystalline solid in essentially quantitative yield, m.p. 190° C. (with decomposition); νmax 1655, 1612 cm-1 ; δ(d6DMSO); 7.53 (d, 1H), 6.20 (d, 1H), 3.70 (s, 3H), 2.33 (s, 3H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04894455 |
| 出典データセット | uspto-grants-1990_01 |
| ORD ID | ord-75c709617744441185b11998ecb3a51b |
| 出典メモ | uspto-grants-1990_01 |