関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Bromide ion | HCID 259 | — |
| 反応物 | Hydrogen Peroxide | HCID 784 | — |
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Chloroselenobenzene | HCID 21928 | — |
| 反応物 | Benzenesulfinyl chloride | HCID 4190003 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Perbenzoic acid | HCID 523077 | — |
反応手順
The diene (2) of step (B) is treated with a halogenating agent such as phenylselenyl chloride or bromide or phenylsulfinyl chloride, preferably phenylselenyl chloride, in an approximately equimolar ratio in an inert solvent at about -80° C., for approximately 20 minutes; illustrative of such inert solvents are methylene chloride, ether and the like. After a standard workup the product residue is dissolved in an ethereal solvent, chilled to about 0° C. and oxidized with an agent such as 30% hydrogen peroxide or a peroxy acid such as peroxybenzoic acid to yield a halohydrin analog (3).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04894466 |
|---|
| 出典データセット | uspto-grants-1990_01 |
|---|
| ORD ID | ord-87cf1d353afc46b09fcef30e59489fe9 |
|---|
| 出典メモ | uspto-grants-1990_01 |
|---|
