Dichloromethane → HCID 85556110、化合物

反応式

C([NH:8][CH2:9][CH:10]([CH2:12][S:13][CH:14]([CH3:16])[CH3:15])[OH:11])(OC(C)(C)C)=O.C(Cl)[Cl:18]>>[NH2:8][CH2:9][CH:10]([CH2:12][S:13][CH:14]([CH3:16])[CH3:15])[OH:11].[ClH:18]

参加物

反応物 2

HCID 6344Dichloromethane

HCID 131716253HCID 131716253、化合物

生成物 1

HCID 85556110HCID 85556110、化合物

実験手順

BOC-NHCH2CH(OH)CH2SCH(CH3)2 (3.74 g, 0.015 mole) was dissolved in 75 ml CH2Cl2 and occasionally purged with HCl gas over two hours. The solvent was removed in vacuo, and the residue was triturated with Et2O. The solvent was decanted and the residue was stripped to a foam, 2.83 g. IR, NMR, and mass spectral analysis confirmed the structure.

後処理

customoccasionally purged with HCl gas over two hours
customThe solvent was removed in vacuo
customthe residue was triturated with Et2O
customThe solvent was decanted

出典と根拠

ORDレコード: ord-d9dac2abfee148078775f620edc16bb6
出典データセット: uspto-grants-1990_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04895834

反応ノート

読み込み中…

参加物