Ethanethiol → 5-Ethylthio pyrrolidin-2-one

HRID 330501

反応式

HRID 330501 の反応式
[OH:1][CH:2]1[NH:6][C:5](=O)[CH2:4][CH2:3]1.[CH2:8]([SH:10])[CH3:9]>C(OCC)C>[CH2:8]([S:10][CH:5]1[NH:6][C:2](=[O:1])[CH2:3][CH2:4]1)[CH3:9]

参加物

4

反応物 2

HCID 6343EthanethiolHCID 1941485-Hydroxy-2-pyrrolidone

生成物 1

HCID 198687055-Ethylthio pyrrolidin-2-one

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture of 2.8 g of 5-hydroxy-pyrrolidin-2-one in 25 cm3 of ethylmercaptan is made to react for 4 hours at 20° C. with 1.4 g of Amberlite IR 120 H. The mixture is diluted with ethyl ether, the solvent is distilled off, and 2.6 g of the expected product is obtained, m.p. 65°-68° C. after crystallizing from isopropyl ether, m.p. 68°-70° C.

後処理

  1. customto react for 4 hours at 20° C. with 1.4 g of Amberlite IR 120 H
  2. distillationthe solvent is distilled off

出典と根拠

ORDレコード
ord-5324f561b33e4c03b35a3398e078bd53
出典データセット
uspto-grants-1990_01
特許番号
US04897414

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