化工社化工社 化学情報印刷レポート · 研究参考用
2-Propanethiol → 5-Isopropylthio-pyrrolidin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Propanethiol | HCID 6364 | — |
| 反応物 | 5-Hydroxy-2-pyrrolidone | HCID 194148 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 5-Isopropylthio-pyrrolidin-2-one | HCID 19868700 | — |
反応手順
A mixture of 9 g of 5-hydroxy-pyrrolidin-2-one in 40 cm3 of 2-propanethiol and 5 g of Amberlite resin IR 120 H is maintained for 80 hours at ambient temperature. After diluting with ether, filtering, and concentrating under reduced pressure, 8.5 g of the expected product is obtained. m.p. 77°-79° C., crystallized from isopropyl ether. m.p. 85°-87° C. after re-crystallization.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04897414 |
| 出典データセット | uspto-grants-1990_01 |
| ORD ID | ord-305946d9a6094476881ff00344e5235f |
| 出典メモ | uspto-grants-1990_01 |