Ammonia → HCID 54387914、化合物

HRID 330530

反応式

HRID 330530 の反応式
[S:1]1[CH2:7][C:5](=[O:6])[NH:4][C:2]1=[S:3].[Cl:8][C:9]1[CH:19]=[CH:18][C:12]([CH:13]=[CH:14][C:15](=O)C)=[CH:11][CH:10]=1.N.[CH2:21](O)C>>[CH3:21][C:14](=[CH:13][C:12]1[CH:11]=[CH:10][C:9]([Cl:8])=[CH:19][CH:18]=1)[CH:15]=[C:7]1[S:1][C:2](=[S:3])[NH:4][C:5]1=[O:6]

参加物

5

反応物 4

HCID 222AmmoniaHCID 702EthanolHCID 981834-ChlorobenzalacetoneHCID 1201546Rhodanine

生成物 1

HCID 54387914HCID 54387914、化合物

実験手順

A mixture of 1.33 g (0.01 mol) of rhodanine, 1.80 g (0.01 mol) of 4-chlorobenzalacetone, 20 ml of ethanol and 2 ml of aqueous ammonia was heated under reflux for 4 hours. After cooling, the precipitated crystals were recovered by filtration and washed with methanol to give 0.52 g of the desired 5-(α-methyl-4-chlorocinnamylidene)-4-oxo-2-thioxothiazolidine.

後処理

  1. temperaturewas heated
  2. temperatureunder reflux for 4 hours
  3. temperatureAfter cooling
  4. filtrationthe precipitated crystals were recovered by filtration
  5. washwashed with methanol

出典と根拠

ORDレコード
ord-cca7abc450654ffc956a09767c423888
出典データセット
uspto-grants-1990_01
特許番号
US04897406

関連ノート

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