3,3-Bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenol → 3,3-Bis(4-Fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenal

HRID 330651ノート

反応式

HRID 330651 の反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:19]2[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=2)=[C:9]([C:12]2[N:13]=[N:14][N:15]([CH2:17][CH3:18])[N:16]=2)[CH2:10][OH:11])=[CH:4][CH:3]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:19]2[CH:20]=[CH:21][C:22]([F:25])=[CH:23][CH:24]=2)=[C:9]([C:12]2[N:13]=[N:14][N:15]([CH2:17][CH3:18])[N:16]=2)[CH:10]=[O:11])=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 147238243,3-Bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenolHCID 178418287HCID 178418287、化合物

生成物 1

HCID 147238273,3-Bis(4-Fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenal収率 79.7%

実験手順

The reaction of 4.0 g (12.0 mmoles) of 3,3-bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenol with pyridinium chlorochromate (4.5 g) was carried out by the procedure described in Example 48 and there was thereby produced 3.25 g (79.7%) of the title compound; m.p.=138°-139° C.

出典と根拠

ORDレコード
ord-021f03ccb8284de3978ae9cf6ed89274
出典データセット
uspto-grants-1990_01
特許番号
US04897490

反応ノート

読み込み中…