1-Bromopropane → 1-Bromo-2-methoxy-4-propoxybenzene
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[O:9][CH3:10].Br[CH2:12][CH2:13][CH3:14].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C.O>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:12][CH2:13][CH3:14])=[CH:4][C:3]=1[O:9][CH3:10]参加物
6
反応条件
- 温度
- 80 °C
実験手順
1.50 g (7.39 mmol) 4-bromo-3-methoxy-phenol are added to 1.36 g (11.1 mmol) 1-bromopropane in 10 mL DMF. 2.04 g (14.8 mmol) K2CO3 are added and the mixture is stirred at 80° C. for 12 h. After that time, the mixture is diluted with water and extracted with DCM. The organic layer is dried over sodium sulphate and the solvent is removed in vacuo.
後処理
- extractionextracted with DCM
- dry with materialThe organic layer is dried over sodium sulphate
- customthe solvent is removed in vacuo
出典と根拠
- ORDレコード
- ord-9a1efe617e9941eab7eea8d90018e4c0
- 出典データセット
- uspto-grants-2014_11
- 特許番号
- US08877754B2
反応ノート
読み込み中…