Hydrochloric Acid → 2-(Piperazin-1-yl)benzo[d]oxazole hydrochloride
反応式
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[O:15][C:16]3[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=3[N:18]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:23]>O1CCOCC1>[ClH:23].[N:11]1([C:14]2[O:15][C:16]3[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=3[N:18]=2)[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1参加物
4
実験手順
10.8 mmol of 4-benzoxazol-2-yl-piperazine-1-carboxylic acid tert.-butyl ester were treated with 30 ml of a dioxane, saturated with gaseous hydrochloric acid. The heterogenous mixture was stirred at room temperature for 1 hour, before evaporation of the solvent. This yielded the title compound as a colorless solid.
出典と根拠
- ORDレコード
- ord-e7c2240539a344748471d5aeb8b8f0b0
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07429585B2
反応ノート
読み込み中…