Water → 4-(4-Nitrophenyl)morpholine

HRID 33252

反応式

HRID 33252 の反応式
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.F[C:8]1[CH:13]=[CH:12][C:11]([N+:14]([O-:16])=[O:15])=[CH:10][CH:9]=1.O>CS(C)=O>[N+:14]([C:11]1[CH:12]=[CH:13][C:8]([N:1]2[CH2:6][CH2:5][O:4][CH2:3][CH2:2]2)=[CH:9][CH:10]=1)([O-:16])=[O:15]

参加物

5

反応物 3

HCID 962WaterHCID 8083MorpholineHCID 9590p-Fluoronitrobenzene

生成物 1

HCID 252224-(4-Nitrophenyl)morpholine

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

反応条件

温度
100 °C

実験手順

A mixture of 24.5 g morpholine and 13.3 g 1-Fluoro-4-nitro-benzene in 30 ml DMSO was heated to 100° C. for 4 h. This solution was poured on to 300 ml of water and the resulting precipitate was collected by filtration to yield a bright yellow crystalline product, which was dried in vacuo.

後処理

  1. filtrationthe resulting precipitate was collected by filtration
  2. customto yield a bright yellow crystalline product, which
  3. customwas dried in vacuo

出典と根拠

ORDレコード
ord-c1072cb05350480f9b5edd1aa57fc23c
出典データセット
uspto-grants-2008_09
特許番号
US07429581B2

関連ノート

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