Trimethylsilyldiazomethane → Methyl 5-formyl-2-furoate

HRID 332587

反応式

HRID 332587 の反応式
[CH:1]([C:3]1[O:7][C:6]([C:8]([OH:10])=[O:9])=[CH:5][CH:4]=1)=[O:2].[CH3:11][Si](C=[N+]=[N-])(C)C>CC(C)=O>[CH3:11][O:9][C:8]([C:6]1[O:7][C:3]([CH:1]=[O:2])=[CH:4][CH:5]=1)=[O:10]

参加物

4

反応物 2

HCID 167693TrimethylsilyldiazomethaneHCID 27937195-Formyl-2-furancarboxylic Acid

生成物 1

HCID 12283779Methyl 5-formyl-2-furoate

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

5-Formyl-2-furancarboxylic acid (5 g, 35.7 mmol) was dissolved in acetone (100 mL), and trimethylsilyl-diazomethane/2M hexane solution (23.2 mL, 46.4 mmol) was slowly added dropwise at room temperature. After stirring at room temperature for 10 minutes, the solvent was evaporated under reduced pressure to give 5-formyl-2-furancarboxylic acid methyl ester as a crude product.

後処理

  1. customthe solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-f7bcdd8ed3a44b75afc4740aea08f9ad
出典データセット
uspto-grants-2014_11
特許番号
US08877805B2

関連ノート

読み込み中…