5-Hydroxymethyl-3-furancarboxylic acid ethyl ester → Ethyl 5-formylfuran-3-carboxylate
反応式
[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[C:9]([CH2:11][OH:12])[O:8][CH:7]=1)=[O:5])[CH3:2]>ClCCl.[O-2].[O-2].[Mn+4]>[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[C:9]([CH:11]=[O:12])[O:8][CH:7]=1)=[O:5])[CH3:2]参加物
4
実験手順
5-Hydroxymethyl-3-furancarboxylic acid ethyl ester (0.34 g, 2.0 mmol) was dissolved in dichloromethane (20 mL), manganese dioxide (1.4 g, 15.9 mmol) was added, and the mixture was stirred overnight. The reaction mixture was filtered through celite, and the solvent was evaporated under reduced pressure to give the title compound (0.26 g).
後処理
- filtrationThe reaction mixture was filtered through celite
- customthe solvent was evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-a5af19dec599455f9b009cffcde12477
- 出典データセット
- uspto-grants-2014_11
- 特許番号
- US08877805B2
反応ノート
読み込み中…