Ethanol → Salicylideneaniline
反応式
[CH:1](=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[NH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.C(O)C>Cl.O>[CH:1](=[N:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4]参加物
6
実験手順
To a mixture of salicylaldehyde (40 mL, 45.84 g, 375.37 mmol)) and aniline (22 mL, 31.72 g, 374.66 mmol), was added ethanol (90 mL), 8 drops of concentrated hydrochloric acid and water (10 mL). This reaction mixture was refluxed for one hour, allowed to cool to room temperature and left in the refrigerator over the weekend. A large quantity of orange solid was formed after 2 hours in the refrigerator. It was filtered off and washed with ethanol. Recrystallisation from ethanol afforded 31.53 g of product.
後処理
- temperatureThis reaction mixture was refluxed for one hour
- waitleft in the refrigerator over the weekend
- customA large quantity of orange solid was formed after 2 hours in the refrigerator
- filtrationIt was filtered off
- washwashed with ethanol
- customRecrystallisation from ethanol
出典と根拠
- ORDレコード
- ord-38c3cae2d5314cb29705c56f787692e9
- 出典データセット
- uspto-grants-2014_11
- 特許番号
- US08883325B2
反応ノート
読み込み中…