(4-Fluoro-3-methylphenyl)boronic acid → 1-(4-Fluoro-3-methyl-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid

HRID 334014

反応式

HRID 334014 の反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5](B(O)O)=[CH:4][C:3]=1[CH3:11].[NH:12]1[CH:16]=[N:15][C:14]([C:17]([O:19]C)=[O:18])=[N:13]1.ClC1C=C(N2C=NC(C(O)=O)=N2)C=CC=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:12]2[CH:16]=[N:15][C:14]([C:17]([OH:19])=[O:18])=[N:13]2)=[CH:4][C:3]=1[CH3:11]

参加物

4

反応物 3

HCID 2774580(4-Fluoro-3-methylphenyl)boronic acidHCID 713019271-(3-Chlorophenyl)-1H-1,2,4-triazole-3-carboxylic acidHCID 178499122HCID 178499122、化合物

生成物 1

HCID 866882411-(4-Fluoro-3-methyl-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid

実験手順

This intermediate was prepared from 4-fluoro-3-methylphenylboronic acid and methyl 1,2,4-triazole-3-carboxylate in two steps according to the preparation of 1-(3-chloro-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid.

出典と根拠

ORDレコード
ord-e9e542b5665247388e662b49da6cfc57
出典データセット
uspto-grants-2014_11
特許番号
US08883789B2

関連ノート

読み込み中…