2-Fluoroaniline → 2-(2-Fluoro-phenyl)-2H-tetrazole-5-carboxylic acid

反応式

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH2:8].ClC1C=C([N:16]2N=[N:19][C:18]([C:21]([OH:23])=[O:22])=[N:17]2)C=CC=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[N:16]=[N:17][C:18]([C:21]([OH:23])=[O:22])=[N:19]1

参加物

反応物 2

HCID 95842-Fluoroaniline

HCID 664909762-(3-Chloro-phenyl)-2H-tetrazole-5-carboxylic acid

生成物 1

HCID 664909862-(2-Fluoro-phenyl)-2H-tetrazole-5-carboxylic acid

実験手順

This intermediate was prepared from 2-fluoro-phenylamine in four steps according to the preparation of 2-(3-chloro-phenyl)-2H-tetrazole-5-carboxylic acid.

出典と根拠

ORDレコード: ord-39973badd39644aca9dca425554fdac7
出典データセット: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08883789B2

反応ノート

読み込み中…