関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 4-Amino-2,6-dichloropyridine | HCID 137652 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 生成物 | 2-Chloro-6-methoxypyridin-4-amine | HCID 71302512 | — |
反応手順
To a solution of 1.84 g (44.0 mmol) sodium in 40 mL MeOH was added 6.72 g (40.0 mmol) 2,6-dichloro-pyridin-4-ylamine. The reaction mixture was stirred at 150° C. for 30 min under microwave irradiation. The solvent was evaporated and ice water was added. The precipitate was filtered off, washed with water and dried.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08883789B2 |
|---|
| 出典データセット | uspto-grants-2014_11 |
|---|
| ORD ID | ord-6e476dc327cb4e6db5cc1ade55d580b7 |
|---|
| 出典メモ | uspto-grants-2014_11 |
|---|
