化工社化工社 化学情報印刷レポート · 研究参考用
NoName_3327 → 1h-Indazole-4-diazonium tetrafluoroborate salt
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | NoName_3327 | HCID 413085 | — |
| 反応物 | Sodium Tetrafluoroborate | HCID 4343483 | — |
| 反応物 | Sodium Nitrite | HCID 23668193 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1h-Indazole-4-diazonium tetrafluoroborate salt | HCID 57420339 | — |
反応手順
An aqueous solution of sodium nitrite (337 mg, 4.89 mmol) in water (2 mL) was added dropwise to a suspension of 1H-indazol-4-ylamine D (631 mg, 4.74 mmol) in 6M hydrochloric acid (7.2 mL) at below 0° C. After stirring for 30 minutes, sodium tetrafluoroborate (724 mg) was added to the reaction mixture. A viscous solution resulted, which was filtered and washed briefly with water to yield 1H-indazole-4-diazonium tetrafluoroborate salt E (218 mg, 20%) as a deep red solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08883799B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-42981412a1274b2d9a09ad31dc0d4098 |
| 出典メモ | uspto-grants-2014_11 |