関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | P-Chloroacetophenone | HCID 7467 | — |
| 反応物 | N,N,N-trimethyl-1,1-bis(1-methylethoxy)amine | HCID 87682 | — |
| 生成物 | (E)-1-(4-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one | HCID 5375260 | — |
反応手順
A solution of 1-(4-chlorophenyl)ethan-1-one (3.0 g, 19.3 mmol) and N,N, dimethylformamide diisopropylacetal (20 ml) was heated at 150° C. for 16 hours. The reaction mixture was cooled to 0° C. and treated with hexanes (20 ml). The resulting solid was collected via filtration and washed with hexanes to provide the title compound: EI-MS (m/z) 209 [M+1]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07429599B2 |
|---|
| 出典データセット | uspto-grants-2008_09 |
|---|
| ORD ID | ord-631ef89be47649218b1ad42fd4234d81 |
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| 出典メモ | uspto-grants-2008_09 |
|---|
