Potassium Carbonate → HCID 178527862、化合物

HRID 33442

反応式

HRID 33442 の反応式
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1)=O.[NH2:15][C:16]([NH2:18])=[S:17].C(=O)([O-])[O-].[K+].[K+]>C(O)C>[Cl:13][C:10]1[CH:11]=[CH:12][C:7]([C:5]2[CH:4]=[CH:3][N:18]=[C:16]([SH:17])[N:15]=2)=[CH:8][CH:9]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 2723790ThioureaHCID 5375260(E)-1-(4-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one

生成物 1

HCID 178527862HCID 178527862、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
85 °C

実験手順

To a solution of (2E)-3-(dimethylamino)-1-(4-chlorophenyl)prop-2-en-1-one (1.5 g, 7.2 mmol) in ethanol (25 ml) was added thiourea (0.60 g, 7.9 mmol) and potassium carbonate (K2CO3) (1.19 g. 8.63 mmol). The resulting suspension was heated to 85° C. for 12 hours then cooled to ambient temperature. The resulting solid was collected and thoroughly washed with water and hexanes to provide a beige solid: EI-MS (m/z) 222 [M+1]+.

後処理

  1. temperaturethen cooled to ambient temperature
  2. customThe resulting solid was collected
  3. washthoroughly washed with water and hexanes
  4. customto provide a beige solid

出典と根拠

ORDレコード
ord-04cd413572fc4b22bcaf1d6a668ae6be
出典データセット
uspto-grants-2008_09
特許番号
US07429599B2

関連ノート

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