化工社化工社 化学情報印刷レポート · 研究参考用
3-Butyn-1-OL → 2-(but-3-ynyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Butyn-1-OL | HCID 13566 | — |
| 反応物 | 1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one | HCID 81431 | — |
| 生成物 | 2-(but-3-ynyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one | HCID 63656448 | 26.3% |
反応手順
The title compound was prepared in accordance with the general method of Example 109(D), from [1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (405 mg, 3.00 mmol) and but-3-yn-1-ol (200 mg, 2.85 mmol). The crude residue was purified by flash chromatography (DCM/MeOH 99:1) to yield 140 mg (0.75 mmol, 26%) of 2-(but-3-ynyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08883826B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-d2f00c29b19a4b5bac7b4213c8884cab |
| 出典メモ | uspto-grants-2014_11 |