Propanal → 1-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-2-propylidenehydrazine

HRID 335479

反応式

HRID 335479 の反応式
[CH2:1]([C:3]1[CH:8]=[C:7]([CH3:9])[CH:6]=[C:5]([CH2:10][CH3:11])[C:4]=1[C:12](=[O:17])[C:13]([NH:15][NH2:16])=[O:14])[CH3:2].[CH:18](=O)[CH2:19][CH3:20]>CO>[CH2:1]([C:3]1[CH:8]=[C:7]([CH3:9])[CH:6]=[C:5]([CH2:10][CH3:11])[C:4]=1[C:12](=[O:17])[C:13]([NH:15][N:16]=[CH:18][CH2:19][CH3:20])=[O:14])[CH3:2]

参加物

4

反応物 2

HCID 527PropanalHCID 569428732-(2,6-Diethyl-4-methylphenyl)-2-oxoacetohydrazide

生成物 1

HCID 666916141-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-2-propylidenehydrazine

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a 100 mL volume three-necked flask, 10.0 g of 2-(2,6-diethyl-4-methylphenyl)-2-oxoacetohydrazide ((12-1)-(11)-39), 38 ml of methanol and 6.16 ml of propanal were added and the mixture was stirred at room temperature for 2 hours. The reaction mixture was concentrated under reduced pressure. The residue was washed with hexane and dried under reduced pressure to give 9.44 g of 1-[2-(2,6-diethyl-4-methylphenyl)-2-oxoacetyl]-2-propylidenehydrazine ((40-a)-(14)-3).

後処理

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. washThe residue was washed with hexane
  3. customdried under reduced pressure

出典と根拠

ORDレコード
ord-45de5542c7a34e6e9436d37725e6e886
出典データセット
uspto-grants-2014_11
特許番号
US08884010B2

関連ノート

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