化工社化工社 化学情報印刷レポート · 研究参考用
Anthranilamide → 2-[4-(4-Oxidanylidene-3h-Quinazolin-2-Yl)phenoxy]ethanoic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Anthranilamide | HCID 6942 | — |
| 反応物 | Acetic acid, 2-(4-formylphenoxy)- | HCID 89177 | — |
| 反応物 | 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one | HCID 136037998 | — |
| 生成物 | 2-[4-(4-Oxidanylidene-3h-Quinazolin-2-Yl)phenoxy]ethanoic Acid | HCID 135566659 | 73% |
反応手順
2-(4-(4-Oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetic acid was synthesized from anthranilamide and 4-formyl phenoxy acetic acid, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(4-(4-Oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetic acid (800 mg, 73%) was isolated as a white solid. Selected data: MS (m/z): 296.98; MP 285-287° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08889698B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-0723a2b089064791b68c9f6968fce0ec |
| 出典メモ | uspto-grants-2014_11 |