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HRID 337154作成日:2026年10月26日

(2Z)-3-(2-cyanophenyl)prop-2-enoic acid → 3-(2-Cyanophenyl)propanoic acid

https://huagongshe.com/reaction/337154

反応式

関与物質

役割名称HCID仕込み量
反応物(2Z)-3-(2-cyanophenyl)prop-2-enoic acidHCID 1899166—
反応物HCID 178418361HCID 178418361—
触媒PalladiumHCID 23938—
溶媒EthanolHCID 702—
生成物3-(2-Cyanophenyl)propanoic acidHCID 1239885090.7%

反応手順

A slurry of (Z)-3-(2-cyanophenyl)acrylic acid (Example 323a, 4.75 g) in ethanol (50 mL) was added to 5% Palladium (0.292 g) in ethanol (50 mL) and hydrogenated under 2.0 bar hydrogen pressure for 2 h. The reaction mixture was filtered and the filtrate evaporated to dryness to afford the sub title compound as a solid (4.36 g).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08889692B2
出典データセットuspto-grants-2014_11
ORD IDord-2a6afa11b5114cea90721941c661a8bc
出典メモuspto-grants-2014_11