関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Dichloromethane | HCID 6344 | — |
| 反応物 | Chloroacetyl chloride | HCID 6577 | — |
| 反応物 | 9,10-Dihydroanthracene | HCID 11940 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1,1'-(9,10-Dihydroanthracene-2,6-diyl)bis(2-chloroethanone) | HCID 86723326 | — |
反応手順
To a stirred solution of 2-chloroacetyl chloride (3.53 mL, 44.4 mmol) and aluminum trichloride (5.92 g, 44.4 mmol) in dichloromethane (DCM) (50 mL), 9,10-dihydroanthracene (2 g, 11.10 mmol) in dichloromethane (DCM) (50 mL) was added dropwise over 5 min at r.t. and left stirring for 1 h. The reaction mixture was then added to a mixture of methanol (100 mL) and H2O (100 mL) chilled to −5° C. The slurry was warmed to ambient temperature, stirred for 30-60 min. and the solids were collected and were washed well with H2O and dried at 50-60° C. to constant weight.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08889726B2 |
|---|
| 出典データセット | uspto-grants-2014_11 |
|---|
| ORD ID | ord-2803a309e3b9455db086b81d73f5e923 |
|---|
| 出典メモ | uspto-grants-2014_11 |
|---|
