Benzamide, N-methoxy-N-methyl-4-(2-quinolinylmethoxy)- → 2,3-Difluoro-N-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide

HRID 33850

反応式

HRID 33850 の反応式
[CH3:1][O:2][N:3](C)[C:4](=O)C1C=CC(OCC2C=CC3C(=CC=CC=3)N=2)=CC=1.[F:25][C:26]1[C:34]([F:35])=[C:33]([O:36][CH2:37][C:38]2[CH:47]=[CH:46][C:45]3[C:40](=[CH:41][CH:42]=[CH:43][CH:44]=3)[N:39]=2)[CH:32]=[CH:31][C:27]=1[C:28]([OH:30])=O>>[F:25][C:26]1[C:34]([F:35])=[C:33]([O:36][CH2:37][C:38]2[CH:47]=[CH:46][C:45]3[C:40](=[CH:41][CH:42]=[CH:43][CH:44]=3)[N:39]=2)[CH:32]=[CH:31][C:27]=1[C:28]([N:3]([O:2][CH3:1])[CH3:4])=[O:30]

参加物

3

反応物 2

HCID 44234674Benzamide, N-methoxy-N-methyl-4-(2-quinolinylmethoxy)-HCID 685762942,3-Difluoro-4-(quinolin-2-ylmethoxy)-benzoic acid

生成物 1

HCID 862492832,3-Difluoro-N-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide

実験手順

Following the procedure for the preparation of N-Methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide but substituting 2,3-Difluoro-4-(quinolin-2-ylmethoxy)-benzoic acid provided the title compound. MS: (M+H m/z=359.1).

出典と根拠

ORDレコード
ord-1d499d424ee24cbcba9f7f72cf1db389
出典データセット
uspto-grants-2008_09
特許番号
US07429665B2

関連ノート

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