5-(4-chlorophenyl)-3,4-dihydro-2H-pyran → 3-(4-chlorophenyl)tetrahydro-2H-pyran
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH2:9][CH2:10][CH2:11][O:12][CH:13]=2)=[CH:4][CH:3]=1.[H][H]>C(OCC)(=O)C.[Pt]=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH2:9][CH2:10][CH2:11][O:12][CH2:13]2)=[CH:6][CH:7]=1参加物
5
実験手順
To a solution of 5-(4-chlorophenyl)-3,4-dihydro-2H-pyran (350 mg, 1.80 mmol) in ethyl acetate (8 mL) was added platinum oxide (41 mg, 0.18 mmol) and the reaction was charged with a hydrogen ballon and stirred at room temperature for 6 hours. The reaction was filtered, and the filtrate was evaporated to give crude title compound (340 mg, 96.3%) as white solid.
後処理
- filtrationThe reaction was filtered
- customthe filtrate was evaporated
出典と根拠
- ORDレコード
- ord-ad21d61a0f6e4810a60ea3fe1bdac0de
- 出典データセット
- uspto-grants-2014_11
- 特許番号
- US08889730B2
反応ノート
読み込み中…